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李时珍从小对医学和本草就有着浓厚的兴趣，长大后因医术高超和楚王举荐而进入北京太医美容院职员曾小雨（郑裕玲 饰）贪恋演员男友，但无奈后者只把她当做佣人对待，惨遭劈腿的曾小雨伤心落魄，去朋友的聚会上寻找新欢，由此机缘巧合结识了富豪之子利志（钟镇涛 饰）。利志父亲因与人斗法，被对手张山以生命为代价化为青面鬼下降头诅咒利家绝子绝孙，这导致利志不能与女性正常接触，而在结合时则会马上丧命。曾小雨昔日同学沈慈航（万梓良 饰）勘破小雨命中定数，赠送驱邪彩带护身。曾小雨与利志初次接触便遭遇车祸，但在朋友们的撮合下，曾、利二人还是展开了交往，沈慈航出面警告二人，情路艰辛，但曾小雨与利志决定继续交往……古代的女主Karagade是个美丽, 但性格歹毒的千金小姐,；主动回避，若没事也显得不明不白了。原来是他，这一刻子夜觉得这位年轻的尹将军实至名归。Yu Ying told the surprised Shengmei that she was Wang Caixiu's girlfriend. Shengmei told her that she was Caixiu's fiancee and asked Shengmei to leave immediately with something. Feeling cheated, Yu Ying came to Caixiu, threw the food he bought on Caixiu and slapped him angrily. Yi Shang walked into the prosecutor's office with the document and met Yu Ying who ran out crying. Yu Ying cried with Yishang in her arms. Yishang took her to see the sea. Youmei happened to see the health and Qinglan who were dating in the market and told Koko about this. Koko urged Health to bring Qinglan to see her as soon as possible. Cai Xiu saw that Yu Ying had not answered the phone, so he called Fan Ren and called Yu Ying out. Cai Xiu knelt in front of Ying and begged her to find Shengmei to explain their relationship. Yu Ying kicked Cai Xiu away with her feet.